Daniel N Cortright Selected Research

N,N- bis(1,3- benzodioxol- 5- ylmethyl)- 1- butyl- 2,4- diphenyl- 1H- imidazole- 5- methanamine

12/2008

Identification and characterization of NDT 9513727 [N,N-bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-imidazole-5-methanamine], a novel, orally bioavailable C5a receptor inverse agonist.

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Daniel N Cortright Research Topics

Disease

7	Pain (Aches) 01/2009 - 01/2003
4	Inflammation (Inflammations) 01/2009 - 01/2003
1	Macular Degeneration (Age-Related Maculopathy) 01/2009
1	Edema (Dropsy) 12/2008
1	Hyperalgesia 12/2008
1	Hypersensitivity (Allergy) 12/2008
1	Neutropenia 12/2008
1	Acquired Immunodeficiency Syndrome (AIDS) 05/2007
1	Intractable Pain 05/2007
1	Migraine Disorders (Migraine) 05/2007
1	Neoplasms (Cancer) 05/2007

Drug/Important Bio-Agent (IBA)

4	Analgesics (Analgesic Drugs)IBA 01/2009 - 01/2007
2	Ion Channels (Ion Channel)IBA 01/2009 - 01/2005
2	TRPV Cation ChannelsIBA 08/2007 - 01/2005
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2009
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2009
1	Opiate AlkaloidsIBA 01/2009
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2009
1	Anaphylatoxin C5a ReceptorIBA 01/2009
1	benzamideIBA 12/2008
1	N,N- bis(1,3- benzodioxol- 5- ylmethyl)- 1- butyl- 2,4- diphenyl- 1H- imidazole- 5- methanamineIBA 12/2008
1	CarrageenanIBA 12/2008
1	LipopolysaccharidesIBA 12/2008
1	Interleukin-6 (Interleukin 6)IBA 12/2008
1	cinnamaldehyde (cinnamic aldehyde)FDA Link 08/2007
1	Menthol FDA Link 08/2007
1	gingerolIBA 08/2007
1	Freund's AdjuvantIBA 01/2007
1	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 01/2003
1	Formaldehyde (Formol)FDA Link 01/2003

Therapy/Procedure

2	Therapeutics 09/2008 - 01/2005
1	Ligation 12/2008
1	Analgesia 09/2008